Caffeine may be the most popular legal addictive stimulant that is available to mankind. Besides coffee, tea, guarana and kola nut have excess amount of this xanthine alkaloid, which is actually acting as a psychoactive drug. In several plants, caffeine is an effective insect repellant, but this trimethylxanthine is deemed by the Food and Drug Administration as generally safe food substance. It is an antagonist of adenosine receptors. The effect of caffeine is individual and may more or less increase the ability to perform physical and mental labor. It reduces the effects of fatigue and may in long term help predominantly men reduce the risk of developing Parkinson’s disease. It has also been observed that caffeine has nootropic effects, furthermore, regular consumption of caffeine may significantly reduce the risk of heart diseases.

Chromium Polynicotinate is a product associated with medical food. It is used as a nutritional support in diabetes related conditions. Chromium polynicotinate is said to be nothing but an assimilated form of chromium. It is said to be the most effective type of chromium. It is absorbed by the body in its biologically active form. It is also crucial to the process of synthesis of fats, protein and cholesterol. Chromium polynicotinate if taken in monitored dosage can help stabilize blood sugar levels. This proves beneficial for people suffering from diabetes as well as hypoglycemia. Its main property is to produce insulin. Therefore, it helps in the metabolism of glucose. This type of chromium polynicotinate helps in the production of anabolic effects which have no side effects. On the other hand, they help in keeping the fat cells away from the muscle cells.

Cocoa Seed Extract, which is standardized for caffeine, tyramine, phenylethylamine and theobromine. Cocoa seed extract is thought to possibly help speed up the metabolism and provide feelings of fullness.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Garcinia Cambogia, which is used for the active ingredient, Hydrocitric Acid or HCA. It is extracted from the garcinia cambogia fruit, similar to an orange. It is commonly used as an appetite suppressant. Hydrocitric acid or HCA is a "lipogenesis inhibitor," which means that it slows down the production of fat from the metabolism of carbohydrates and proteins. This means that more calories are burned as energy and less are turned into stored fat. Studies on animals and humans have shown that HCA can suppress fat production and reduce appetite.

Ginger Root refers to the rhizome of a plant called zingiber officinale that grows in moist and fertile tropical soil. Ginger is an underground stem extending to 12 inches above the ground. The ginger root has pungent phenol compounds and volatile oils. This is widely used as a medicine in Indian, Asian and Arabic herbal traditions. Ginger, in China is used to cure stomach upset, nausea and diarrhea since ancient times. Ginger is of great use to cure arthritis, diarrhea, Colic and heart conditions. Besides the medicinal value, Ginger is one of the indispensable ingredients as cooking spice and is also recommended to cure headaches, common cold, symptoms like flu and also painful menstrual periods. Ginger is widely used as medicine as it treats nausea, vomiting related to travel sickness, cancer chemotherapy and pregnancy. Though, there are effective medicines today, ginger root retain its position for its medicinal properties. It is also beneficial for heart disease as it reduces cholesterol and averts blood clotting. The ginger products are manufactured using dried or fresh ginger root and these are obtainable in extracts, capsules, tinctures and oils. Ginger is used in tea and in various drinks and foods.

Green Tea Extract is of immense use to treat body ache, headaches and poor digestion. The green tea extract contains polyphenols to high levels and is an opulent source of antioxidant. It has the power of fighting free radicals more than vitamin E. the polyphenols present in green tea extract protect against respiratory and digestive infections. It blocks the carcinogens actions that promotes cancer and reduces the cholesterol levels. Green tea extract helps in metabolizing fat. The dieters can feel the weight loss without side effects and jitters. The green tea extract decreases the heart disease risk and also helps in preventing liver failure. The benefits of green tea extract are many, but as it contains caffeine, medical experts should be consulted prior to using it. Green tea extract also defends dental plaque. Green tea extracts prevents even liver transplant failure, but pregnant women should take green tea only after doctor consultation.

Guarana, a stimulant derived from the seeds of the Brazilian Guarana plant. Guarana is used to increase alertness and help fight fatigue. It contains caffeine and is usually associated with an "energy crash" several hours after taking a large dose.

Hoodia Gordonii is an extract from the Hoodia plant of South West Africa. It is one of the fore runners in weight loss programs. Quenching thirst and providing energy are two of the numerous uses of the plant extract. The extract reduces gastric acid output in the stomach to a large extent, ranging from 40 – 60%. Aside from repressing hunger, Hoodia raises the overall energy levels in the body and will make a person feel completely healthy – both mentally and physically. Hoodia Gordonii is known to be extremely effective and does not have side effects such as dizziness, causing an increase of the heart beat or body temperature and sleeplessness. Hoodia Gordonii, however, should not be used during pregnancy and by nursing mothers.

Hordenine, which is also known as N-Dimethyl-hydroxyphenylethylamine, is a phenylethylamine alkaloid, which naturally occurs in barley seeds, but also in several cactus plants. The phenomenal antibiotic and antibacterial properties have long been recognized by the medical community, where in particular penicillin resistant Staphylococcus bacteria can be successfully restrained. Hordenine stimulates norepinephrine release and is therefore deemed a direct central nervous system stimulant. Norepinephrine, in turn, is a hormone that works as a lipolytic, aiding in liberating the stored fat from the cells and make it available for burning during the workout. The body building community commonly uses Hordenine as a weight loss agent. Furthermore, it seems that Hordenine is slowing down the digestive process, thereby slowing down the calorie transfer, allowing the excess fat to be burned, while retaining the feeling of satiation.

L-Tyrosine is a proteinogenic polar amino acid, deemed not essential because it can be synthesized by the human body. As a member of the amino acid group that is being used by cells to build proteins, this building block derived its name from the Greek word tyros, which means cheese, because it was discovered in the cheese protein casein. L-Tyrosine can be synthesized from phenylalanine and can be found in foods high on protein, like soy products, poultry, cheese, bananas, dairy products and several seeds, including the sesame seeds. The unique phenol functionality and the occurrence in proteins that belong to the signal transduction process, make this amino acid different. Tyrosine can be converted by tyrosine hydroxylase enzyme into levodopa, a psychoactive drug that is used, among other uses, for clinical treatment of Parkinson’s disease. It is also involved in the synthesis of dopamine, norepinephrine and epinephrine.

Octopamine is a biogenic substance which is containing an amine group, apparently related to noradrenaline, which is a catecholamine functioning as both, neurotransmitter and a hormone. Similar to norepinephrine, which is another name for noradrenaline, octopamine may act as a stress hormone, triggering increased heart rate, energy consumption and blood flow, even the blood pressure. One side effect of octopamine is apparently the release of fat from the adipocytes, which are the fat cells where excess energy is being stored. This side effect prompted the use of octopamine as a dietary supplement aimed at weight loss, but used in combination with other stimulants. Octopamine has been discovered in the middle of the twentieth century, but the use as a fat removal agent is very recent.

Pantothenic Acid is actually a part of the Vitamin B complex, namely Vitamin B5 and is deemed an essential nutrient. It has a critical function in the synthesis and metabolism of core nutrients, such as fats, proteins and carbohydrates, and it forms the coenzyme – A, also called CoA, most notable for the role in oxidation and synthesis of fatty acids and pyruvate. The Greek origin of the name Pantothenic Acid already states that this Vitamin is found nearly everywhere, with prominent amounts in eggs, meat, legumes and whole grain cereals. In health and fitness circles the dietary supplement is very popular for its energy producing role, but also for the ATP process and for the maintenance of cholesterol and triglycerides levels in the body.

Synephrine, More commonly called "bitter orange" or Citrus Aurantium, which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Vinpocetine- The lesser periwinkle plant named Vinca Minore consists of Vincamine, which is found in its leaves and Vinpocetine is derived from this natural substance found in the plant. In countries such as Japan and Europe, Vinpocetine is a prescribed medicine. It is popularly available in the online stores and countries such as Canada and the US as an effective supplement for diet. Vinpocetine is a great medicine in order to protect oneself from brain dementia. It has also been found to help treat Alzheimer’s disease. However, there is no strong recent evidence to prove its effect on the treatment of Alzheimer’s disease. Overall, it’s great to boost the brain. However, it has certain side effects such as anxiety, insomnia, indigestion, dry mouth, headache and many more.

White Willow Bark possesses salicin that offers identical effect as aspirin and exhibits no side effects. This is the basis for aspirin synthesis. Chinese healers used it to control pain and the Native Americans also understood the value of it to get relief from headaches as well rheumatism. This also reduces fevers. The advantage of white willow bark is that it also helps in reducing weight and aids the diet goals. It is an anti-inflammatory and is analgesic, anti-rheumatic, fever reducer and gives relief from inflammatory pains such as rheumatism, carpal tunnel syndrome and arthritis. White willow bark is found in Asia and Europe. Taking one or two capsules at mealtimes is recommended. However, this dosage should not be exceeded. This does not exhibit significant side effects, but the tannins present in the white willow extract may result in stomach upset and may trouble if a person is allergic to aspirin.

Yerba Matte is believed to possess cancer-fighting properties and has shown to have a relaxing effect on muscle tissues and a stimulating effect on heart tissues.